Anti-Tβ-15a/b Antibody (B-4) is a mouse monoclonal IgG2a (kappa light chain) Tβ-15a/b antibody provided at 200 µg/ml
raised against amino acids 1-45 representing full length Tβ-15a of human origin
Anti-T beta-15a/b Antibody (B-4) is recommended for detection of Tβ-15a and Tβ-15b of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-T beta-15a/b Antibody (B-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Tβ-15a/b (B-4): sc-271649.
At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Tβ-15a/b Antibody (B-4). This work is in progress.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Tβ-15a/b Antibody (B-4) is a high quality monoclonal T beta-15a/b antibody (also designated Tβ-15a/b antibody) suitable for the detection of the T beta-15a/b protein of mouse, rat and human origin. Tβ-15a/b Antibody (B-4) is available as both the non-conjugated anti-T beta-15a/b antibody form, as well as multiple conjugated forms of anti-T beta-15a/b antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. β-thymosins are a family of small, water-soluble peptides. They are molecules with multiple and diverse intracellular and extracellular functions. β-thymosins are known for binding G-Actin and disturbing the assembly of F-Actin. Tβ-15a (TMSB15A), also designated neuroblastoma thymosin β (NB Tβ), or thymosin-like protein 8, is significantly similar to its family members thmyosin-β15b (Tβ-15b), thmyosin-β4 (Tβ-4) and thymosin-β10 (Tβ-10). Tβ-15a is a 44 amino acid protein expressed in neuroblastomas that localizes to the cytoplasm. It interacts with G-Actin and is involved in tissue invasion, cell growth and cell motility. Interference of Tβ-15a expression has been shown to decrease cell invasion. Tβ-15a may play a role in tumor development and progression. A newly described isoform of thmyosin-β15, Tβ-15b is transcribed from a different gene (TMSB15B) and encodes a protein identical to Tβ-15a. The two gene isoforms are subject to different transcriptional regulation and have distinct expression.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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