Anti-TANC2 Antibody (D-11) is a mouse monoclonal IgG1 κ TANC2 antibody, cited in 2 publications, provided at 200 µg/ml
raised against amino acids 1534-1737 mapping within an internal region of TANC2 of human origin
Anti-TANC2 Antibody (D-11) is recommended for detection of TANC2 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-TANC2 Antibody (D-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of TANC2 (D-11): sc-515710.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TANC2 Antibody (D-11) for WB applications. These reagents are now offered in bundles with TANC2 Antibody (D-11) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
TANC2 Antibody (D-11) is a high quality monoclonal TANC2 antibody (also designated TANC2 antibody) suitable for the detection of the TANC2 protein of mouse, rat and human origin. TANC2 Antibody (D-11) is available as both the non-conjugated anti-TANC2 antibody form, as well as multiple conjugated forms of anti-TANC2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. TANC2 (tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 2), also known as rolling pebbles homolog B, is a 1,990 amino acid protein that belongs to the TANC family and exists as four alternatively spliced isoforms. TANC2 contains eleven ANK repeats and three TPR repeats. The gene that encodes TANC2 contains 418,170 bases and maps to human chromosome 17q23.3. Encoding over 1,200 genes, chromosome 17 comprises over 2.5% of the human genome. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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