Talniflumate CAS: 66898-62-2
MF: C21H13F3N2O4
MW: 414.34
An inhibitor of Cox and Cl-/HCO3- exchange.

Talniflumate (CAS 66898-62-2)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 138ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Alternativa namn: Lomucin; Somalgen; Talniflumatum
Ansökan Talniflumate is an inhibitor of Cox and Cl-/HCO3- exchange
CAS Nr: 66898-62-2
Renhet: ≥98%
Molekylvikt: 414.34
Molekylär formel: C21H13F3N2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Talniflumate is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and release in animal models and cell culture. Talniflumate possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. Talniflumate increases survival in a cystic fibrosis mouse model of distal intestinal obstructive syndrome.


Konferenser

1. Knight, D., 2004. Curr. Opin. Invest. Drugs. 5: 557-562.
2. Walker, N.M., et al. 2006. J. Pharmacol. Exp. Ther. 317: 275-283.

Physical State :
Solid
Solubility :
Soluble in DMSO (25 mM).
LAGRING :
Store at -20° C
Melting Point :
165-170° C
Boiling Point :
~534.57° C at 760 mmHg (Predicted)
Density :
~1.5 g/cm3 (Predicted)
Refractive Index :
n20D 1.63 (Predicted)
pK Values :
pKb: 2.72 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
QT2999200
PubChem CID :
MDL Number :
MFCD00866135
Beilstein Registry :
0503261
SMILES :
C1=CC=C2C(=C1)C(OC2=O)OC(=O)C3=C(N=CC=C3)NC4=CC=CC(=C4)C(F)(F)F

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 124ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 7ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2021 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.