Sunitinib, Free Base is a free base form of Sunitinib malate salt (sc-220177) which is used for the study of imatinib-resistant gastrointestinal stromal tumor (GIST) cells. Sunitinib malate salt (sc-220177) inhibits c-KIT, Flk-1, Flt-1, Flt-3/Flt-2, Flt-4, PDGRFα, PDGFRβ, c-Fms-CSF-1R, and Ret.
3. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. Motzer RJ et al. N.Engl.J.Med. 356(2), 115–124 (2007)
Crystalline granules or crystalline powder
Soluble in water (very poorly), DMSO (40 mg/ml), and ethanol with warming (1.4 mg/ml).
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