Sp-Adenosine 3prime,5prime-cyclic monophosphorothioate triethylammonium salt CAS: 93602-66-5
MF: C10H11N5O5PS•C6H16N
MW: 446.46
A membrane permeable activator of cAMP dependent protein kinase I and II.

Sp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt (CAS 93602-66-5)

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Alternativa namn: Sp-Cyclic 3',5'-hydrogen phosphorothioate adenosine; Sp-cAMPS triethylammonium salt
Ansökan Sp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt is a membrane permeable activator of cAMP dependent protein kinase I and II
Momsregistreringsnummer :: 93602-66-5
Purity: ≥98%
Molecular Weight: 446.46
Molecular Formula: C10H11N5O5PS•C6H16N
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Sp-Diastereomer of adenosine 3',5'-cyclic monophosphorothioate is a potent, membrane-permeable activator of PKA (cAMP dependent protein kinase I and II). Mimics the effects of cAMP as a second messenger in numerous systems while being resistant to cyclic nucleotide phosphodiesterases. Exhibits greater specificity and affinity than forskolin and cAMP analogs such as dibutyryl-cAMP. Sp-Adenosine 3',5'-cyclic monophosphorothioate triethylammonium salt hydrate is an activator of Epac.

Physical State :
Solid
Solubility :
Soluble in water.
LAGRING :
Store at -20° C
Melting Point :
212-213° C
Optical Activity :
α22/D -25.43°, c = 0.99 in water
pK Values :
pKa: 1 (Predicted), pKb: 3.63 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
57369926
MDL Number :
MFCD01459901
SMILES :
CC[NH+](CC)CC.C1C2C(C(C(O2)N3C=NC4=C3N=CN=C4N)O)OP(=S)(O1)[O-]

Download SDS (MSDS)

Certificate of Analysis

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