SNARK Antibody (E-8) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
raised against amino acids 501-628 mapping at the C-terminus of SNARK of human origin
recommended for detection of SNARK of human origin by WB, IP, IF and ELISA
m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SNARK Antibody (E-8) for WB applications. These reagents are now offered in bundles with SNARK Antibody (E-8) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. SNARK (SNF1/AMP kinase-related kinase), also known as NUAK2 (NUAK family, SNF1-like kinase, 2), is s 628 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Using magnesium as a cofactor, SNARK catalyzes the ATP-dependent phosphorylation of target proteins and is involved in regulating cell tolerance to stress-induced glucose starvation. Additionally, SNARK is thought to induce cell-cell detachment and may protect cells from Fap-1-mediated apoptosis, possibly playing a role in the motility and invasiveness of tumor cells.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
All trademarks are the property of their respective owners.
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn