Anti-SGTA Antibody (6A4) is a mouse monoclonal IgG1 (kappa light chain) SGTA antibody provided at 200 µg/ml
raised against recombinant SGTA of human origin
Anti-SGTA Antibody (6A4) is recommended for detection of SGTA of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-SGTA Antibody (6A4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of SGTA (6A4): sc-130557.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
SGTA Antibody (6A4) is a high quality monoclonal SGTA antibody (also designated SGTA antibody) suitable for the detection of the SGTA protein of mouse, rat and human origin. SGTA Antibody (6A4) is available as both the non-conjugated anti-SGTA antibody form, as well as multiple conjugated forms of anti-SGTA antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. SGTA (small glutamine-rich tetratricopeptide repeat (TPR)-containing protein A or alpha), also known as SGT, hSGT or UBP (Vpu-binding protein), is a ubiquitously expressed protein that contains three TPR protein-protein interaction repeats. SGTA is believed to function as a component of the androgen receptor (AR)-chaperone-co-chaperone complex, acting as a co-chaperone involved in androgen signaling. More specifically, SGTA binds to the hinge region of the AR functions to retain the AR in the cytoplasm, thereby inhibiting androgen signaling. In addition, SGTA functions as a co-chaperone for HSP 90 and HSP 70, two proteins known to participate in apoptosis. On the basis of its role in apoptosis and androgen signaling, SGTA is a potential candidate for PCOS (polycystic ovary syndrome), a disorder characterized by androgen excess, obesity and menstrual disturbances. SGTA also interacts with the nonstructural Parvovirus protein NS1 and the HIV-1 proteins Vpu and Gag.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences