SCH-202676 hydrobromide CAS: 70375-43-8
MF: C15H13N3S·HBr
MW: 348.3
A modulator that inhibits binding to G protein-coupled receptors.

SCH-202676 hydrobromide (CAS 70375-43-8)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 178ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: N-(2,3-diphenyl-1,2,4-thiadiazol-5-(2H)-ylidene)methanamine hydrobromide
Ansökan A modulator that inhibits binding to G protein-coupled receptors
Momsregistreringsnummer :: 70375-43-8
Purity: ≥99%
Molecular Weight: 348.3
Molecular Formula: C15H13N3S·HBr
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

SCH-202676 hydrobromide is a G protein-coupled receptor allosteric modulator that has been shown to inhibit agonist and antagonist binding to a wide range of G protein-coupled receptors that are structurally unrelated. SCH-202676 hydrobromide has displayed divergent effects on purine receptors. It is reported to inhibit radioligand binding to human Adenosine A1-R, A2A-R, and A3-R and thus affects dissociation kinetics.


Konferenser

1. Fawzi, A.B., et al. 2001. Mol. Pharmacol. 59: 30-37. PMID: 11125021
2. Lanzafame, A., et al. 2004. J. Pharmacol. Exp. Ther. 308: 830-837. PMID: 14617684
3. Gao, Z.G., et al. 2004. Life Sci. 74: 3173-3180. PMID: 15081581
4. Lewandowicz, A.M., et al. 2006. Br. J. Pharmacol. 147: 422-429. PMID: 16402041

Physical State :
Solid
Solubility :
Soluble in DMSO (40 mg/ml), water, and ethanol.
LAGRING :
Store at room temperature
Melting Point :
240.0-240.8° C (lit.)
Boiling Point :
423.8° C at 760 mmHg
IC50 :
large T antigen: IC50 = 29.42 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
11957689
MDL Number :
MFCD06671539
SMILES :
CN=C1N=C(N(S1)C2=CC=CC=C2)C3=CC=CC=C3.Br

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 140ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 9ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.