Anti-RGS4 Antibody (H-12) is a mouse monoclonal IgM κ RGS4 antibody, cited in 3 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 182-205 at the C-terminus of RGS4 of human origin
recommended for detection of RGS4 of mouse, rat and human origin by WB, IP, IF and ELISA
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of RGS4 (H-12): sc-398348.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for RGS4 Antibody (H-12) for WB applications. This reagent is now offered in a bundle with RGS4 Antibody (H-12) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
RGS4 Antibody (H-12) is a high quality monoclonal RGS4 antibody (also designated RGP4 antibody) suitable for the detection of the RGS4 protein of mouse, rat and human origin. RGS4 Antibody (H-12) is available as the non-conjugated anti-RGS4 antibody. Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four Gα GTPase-activating proteins (GAPs) have been identified and are designated RGS1 (regulator of G protein signaling), RGS4, RGS10 and GAIP (Gα-interacting protein). Each of these proteins has been shown to deactivate specific Gα isoforms by increasing the rate at which they convert GTP to GDP. RGS1, RGS4 and GAIP bind tightly to and exhibit GAP activity towards Gα i, Gα o and Gα t, but not Gα s. RGS10 increases the GTP hydrolytic activity of several members of the Gα i subfamily including Gα i-3, Gα z and Gα o.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.