RGD peptide (GRGDNP) CAS: 114681-65-1
MF: C23H38N10O10
MW: 614.61
An inhibitor of integrin-ligand interactions.

RGD peptide (GRGDNP) (CAS 114681-65-1)

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Ansökan RGD peptide (GRGDNP) is an inhibitor of integrin-ligand interactions
CAS Nr: 114681-65-1
Renhet: ≥97%
Molekylvikt: 614.61
Molekylär formel: C23H38N10O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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RGD peptide (GRGDNP) acts as an inhibitor of integrin-ligand interactions and can induce apoptosis in the absence of signals and integrin-mediated cell clustering. Research demonstrates that RGD peptides promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. The RGD peptide can serve as a cell adhesion site of extracellular matrix, cell surface proteins, and integrins. In addition, RGD peptide can inhibit ACK-2 activation through cell adhesion.


Konferenser

1. Ruoslahti, E. 1996. Annu. Rev. Cell Dev. Biol. 12: 697-715. PMID: 8970741
2. Meredith, J.E. and Schwartz, M.A. 1997. Trends Cell Biol. 7: 146-150. PMID: 17708932
3. Yang, W., et al. 1999. J. Biol. Chem. 274: 8524-8530. PMID: 10085085
4. Buckley, C.D., et al. 1999. Nature. 397: 534-539. PMID: 10028971

Physical State :
Solid
Sequence :
Gly-Arg-Gly-Asp-Asn-Pro
Solubility :
Soluble in water (>50 mg/ml)
LAGRING :
Store at -20° C
Density :
~1.7 g/cm3 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
C1C[[email protected]](N(C1)C(=O)[[email protected]](CC(=O)N)NC(=O)[[email protected]](CC(=O)O)NC(=O)CNC(=O)[[email protected]](CCCN=C(N)N)NC(=O)CN)C(=O)O

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Certificate of Analysis

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RGD peptide (GRGDNP) (CAS 114681-65-1)  Produkt Citat

See how others have used RGD peptide (GRGDNP) (CAS 114681-65-1). Click on the entry to view the PubMed entry .

Citations 1 to 10 of 12 total

PMID: # 30801249  2019. Elife. 8:

PMID: # 29584619  Pincha, N.|Hajam, EY.|Badarinath, K.|Batta, SPR.|Masudi, T.|Dey, R.|Andreasen, P.|Kawakami, T.|Samuel, R.|George, R.|Danda, D.|Jacob, PM.|Jamora, C.| et al. 2018. J. Clin. Invest. 128: 1807-1819.

PMID: # 29903032  Liu, C.|Qu, L.|Zhao, C.|Shou, C.| et al. 2018. J. Exp. Clin. Cancer Res. 37: 117.

PMID: # 26678556  Mikami, J.|Tobisawa, Y.|Yoneyama, T.|Hatakeyama, S.|Mori, K.|Hashimoto, Y.|Koie, T.|Ohyama, C.|Fukuda, M.| et al. 2016. Cancer Sci. 107: 359-68.

PMID: # 24768768  Gao, M. et al. 2014. Cellular signalling. 26: 2161-6.

PMID: # 24785587  Lee, SH. et al. 2014. Radiat. Res. 181: 650-8.

PMID: # 24843046  Marbiah, MM. et al. 2014. The EMBO journal. 33: 1527-47.

PMID: # 25415317  Carrim, N. et al. 2014. PloS one. 9: e113679.

PMID: # 23145974  Hillman, RD. et al. 2013. Cell. Microbiol. 15: 727-41.

PMID: # 23331249  Chang, IA. et al. 2013. Journal of neurochemistry. 125: 214-24.

Citations 1 to 10 of 12 total
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