Anti-Rab 10 Antibody (2A1C9) is a mouse monoclonal IgG1 κ Rab 10 antibody, cited in 1 publications, provided at 200 µg/ml
raised against a recombinant protein corresponding to amino acids 1-198 of Rab 10 of human origin
recommended for detection of Rab 10 of mouse, rat and human origin by WB and ELISA
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Rab 10 Antibody (2A1C9) for WB applications. These reagents are now offered in bundles with Rab 10 Antibody (2A1C9) (see ordering information below).
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Rab 10 Antibody (2A1C9) is a high quality monoclonal Rab 10 antibody (also designated RAB10 antibody) suitable for the detection of the Rab 10 protein of mouse, rat and human origin. Rab 10 Antibody (2A1C9) is available as the non-conjugated anti-Rab 10 antibody. The Ras-related superfamily of guanine nucleotide binding proteins, which includes the Ral/Rec, Rap, R-Ras, and Rho/Rab subfamilies, exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles. Several members of the Rab subfamily have been identified, each of which is found at a particular stage of a membrane transport pathway (3-8).
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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