(R)-(-)-Niguldipine hydrochloride is an L-type calcium channel protein inhibitor and α1A-AR (α1A-adrenoceptor) antagonist. (R)-(-)-Niguldipine hydrochloride is the less active enantiomer relative to (S)-(+)-Niguldipine hydrochloride (sc-203248).
1. Graziadei, I., et al. 1989. Eur. J. Pharmacol. 172: 329-337. PMID: 2555206
Soluble in methanol, and water (10 mM).
Store at -20° C
n20D ~1.59 (Predicted)
α23/D -12.5°, c = 0.14 in methanol; α20/D -14°, c = 1 in methanol
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