(R)-(-)-Niguldipine hydrochloride CAS: 113145-70-3
MF: C36H39N3O6•HCl
MW: 646.18
A calcium channel protein inhibitor.

(R)-(-)-Niguldipine hydrochloride (CAS 113145-70-3)

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Alternativa namn: (R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester hydrochloride
Ansökan (R)-(−)-Niguldipine hydrochloride is a calcium channel protein inhibitor
CAS Nr: 113145-70-3
Molekylvikt: 646.18
Molekylär formel: C36H39N3O6•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
* Refer to Certificate of Analysis for lot specific data (including water content).

(R)-(-)-Niguldipine hydrochloride is an L-type calcium channel protein inhibitor and α1A-AR (α1A-adrenoceptor) antagonist. (R)-(-)-Niguldipine hydrochloride is the less active enantiomer relative to (S)-(+)-Niguldipine hydrochloride (sc-203248).


Konferenser

1. Graziadei, I., et al. 1989. Eur. J. Pharmacol. 172: 329-337. PMID: 2555206

Physical State :
Solid
Solubility :
Soluble in methanol, and water (10 mM).
LAGRING :
Store at -20° C
Melting Point :
145-148° C
Refractive Index :
n20D ~1.59 (Predicted)
Optical Activity :
α23/D -12.5°, c = 0.14 in methanol; α20/D -14°, c = 1 in methanol
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
WGK Germany :
3
PubChem CID :
MDL Number :
MFCD00083190
SMILES :
CC1=C([[email protected]](C(=C(N1)C)C(=O)OCCCN2CCC(CC2)(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC.Cl

Download SDS (MSDS)

Certificate of Analysis

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