(R)-(-)-Apomorphine hydrochloride is a prototypical dopamine agonist (pKi values are 6.43, 7.08, 7.59, 8.36, and 7.83 for human recombinant D1, D2L, D3, D4 and D5 receptors respectively). (R)-(-)-Apomorphine hydrochloride, produces biphasic effects on locomotor activity, displays antiparkinsonian, and neuroprotective actions when systemically administered in vivo.
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Soluble in water (50 mM), and DMSO (100 mM). and mixes with alcohol (1:50).
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