PTP CD45 Inhibitor (CAS 345630-40-2)

5.0(1)

Alternativa namn: Protein Tyrosine Phosphatase CD45 Inhibitor; N-(9,10-dihydro-9,10-dioxo-2-phenanthrenyl)-2,2-dimethyl-propanamide

Ansökan PTP CD45 Inhibitor is a cell permeable potent reversible inhibitor of CD45

CAS Nr: 345630-40-2

Renhet: ≥97%

Molekylvikt: 307.34

Molekylär formel: C₁₉H₁₇NO₃

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

* Refer to Certificate of Analysis for lot specific data (including water content).

QUICK LINKS

PTP CD45 Inhibitor: sc-222223. Immunofluorescence staining of methanol-fixed lambda protein...

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PTP CD45 Inhibitor is a cell-permeable, potent, selective, competitive, and reversible inhibitor of CD45 (IC₅₀ = 200 nM or 3.8 μM using pNPP or phosphorylated Ick505 peptide as a substrate, respectively). PTP CD45 Inhibitor is not able to effectively inhibit PTPIB (IC₅₀ <30 μM using phosphorylated Ick505 peptide as a substrate). The phenanthrenedione group does not function as a thiol oxidizing agent.

Konferenser

1. Urbanek, R.A., et al. 2001. J. Med. Chem. 44: 1777-1793. PMID: 11356112

Physical State :

Solid

Solubility :

Soluble in DMF (10 mg/ml), and DMSO (10 mg/ml).

LAGRING :

Store at 4° C

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

PubChem CID :

9926586

SMILES :

CC(C)(C)C(=O)NC1=CC2=C(C=C1)C3=CC=CC=C3C(=O)C2=O

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Certificate of Analysis

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PTP CD45 Inhibitor (CAS 345630-40-2) Produkt Citat

See how others have used PTP CD45 Inhibitor (CAS 345630-40-2). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 24231767 Novák, J. et al. 2014. Molecular immunology. 57: 302-9.

Citations 1 to 1 of 1 total

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