PtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt) MF: C47H82O22P4•4Na
MW: 1215

PtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 111ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Alternativa namn: Phosphatidylinositol-3,4,5-triphosphate C-18 (sodium salt)
Molekylvikt: 1215
Molekylär formel: C47H82O22P44Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids, but they play a crucial role in the generation and transmission of cellular signals.PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and Akts are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific PLC. Therefore, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates.


Konferenser

1. Lapetina, E.G., et al. 1981. Nature. 292: 367-369. PMID: 626579
2. Majerus, P.W. 1992. Annu. Rev. Biochem. 61: 225-250. PMID: 1323235
3. Tanaka, K., et al. 1997. Eur. J. Biochem. 245: 512-519. PMID: 9151987
4. Yang, X., et al. 1999. J. Biol. Chem. 274: 18973-18980. PMID: 10383396
5. Pike, L.J. and Casey, L. 1996. J. Biol. Chem. 271: 26453-26456. PMID: 8900109
6. Berridge, M.J. 1993. Nature. 361: 315-325. PMID: 8381210

Appearance :
Powder
Physical State :
Solid
LAGRING :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
SMILES :
CCCCCCCCCCCCCCCCCC(OCC(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COP([O-])(O[[email protected]@H]1[[email protected]](O)[[email protected]](OP([O-])(O)=O)[[email protected]@H](OP([O-])(O)=O)[[email protected]](OP([O-])(O)=O)[[email protected]]1O)=O)=O

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 100ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 5ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2021 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.