Prostaglandin Bx is a mixture of oligomers of PGB1 (sc-201217) with a molecular weight of 1,000-1,500, that has demonstrated anti-inflammatory and cytoprotective activity. This action is thought to be attributed to inhibition of the 14 kDa sPLA2. This compound also has antioxidant and free radical trapping activity, and has been shown to act as a Ca2+ ionophore.
1. Ohnishi, S.T., et al. 1979. Biochem. Biophys. Res. Commun. 89: 240-245. PMID: 113006
2. Polis, B.D., et al. 1979. Proc. Natl. Acad. Sci. U.S.A. 76: 1598-1602. PMID: 287000
3. Kumashiro, R., et al. 1985. Int Surg. 70: 247-250. PMID: 3835168
4. Ohnishi, S.T., et al. 1989. Arzneimittelforschung. 39: 236-239. PMID: 2730694
5. Franson, R.C., et al. 1991. Prostaglandins Leukot. Essent. Fatty Acids. 43: 63-70. PMID: 1886908
6. Hidaka, S., et al. 1992. Cancer Lett. 61: 171-176. PMID: 1730141
Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2021 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.