PRL-3 Inhibitor is a cell-permeable benzylidene rhodanine compound that potently inhibits PRL-3 (hPRL-3), a member of the regenerating liver family tyrosine phosphatases. PRL-3 Inhibitor has been shown to reduce the invasiveness of murine melanoma B16F10 cells.
1. Ahn, J.H., et al. 2006. Bioorg. Med. Chem. Lett. 16: 2996-2999. PMID: 16530413
Soluble in DMSO (5 mg/ml). Slight warming may be necessary for complete solubilization.
Store at -20° C
268.90° C (Predicted)
620.54° C (Predicted)
1.86 g/cm3 (Predicted)
n20D 1.77 (Predicted)
hPRL-3 : IC50 = 900 nM
pKa: 7.11 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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