Anti-PP2A-B55 Antibody (D-10) is a mouse monoclonal IgG1 κ PP2A-B55 antibody, cited in 5 publications, provided at 200 µg/ml
raised against amino acids 148-447 mapping at the C-terminus of PP2A-B55-α of human origin
Anti-PP2A-B55 Antibody (D-10) is recommended for detection of PP2A-B55-α, -β, -γ and -δ isoforms of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
Anti-PP2A-B55 Antibody (D-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of PP2A-B55 (D-10): sc-365282.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PP2A-B55 Antibody (D-10) for WB and IHC(P) applications. These reagents are now offered in bundles with PP2A-B55 Antibody (D-10) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
PP2A-B55 Antibody (D-10) is a high quality monoclonal PP2A-B55 antibody (also designated Serine/Threonine phosphatase PP2A-B55 broad reactivity antibody, PR55A antibody, B55A antibody, PR52B antibody, PR55G antibody, protein phosphatase 2 regulatory subunit B alpha/beta/delta/gamma antibody, protein phosphatase 2 (PP2A) alpha/beta/delta/gamma antibody, PPP2R2A antibody, PPP2R2B antibody, PPP2R2C antibody, PPP2R2D antibody, PP2A B55 subfamily antibody, PP2A heterotrimeric (structural A, regulatory B, catalytic C) protein phosphatase antibody, PP2A phosphatase regulatory B55 antibody, protein phosphatase 2 complex antibody, or Ser/Thr phosphatase antibody) suitable for the detection of the PP2A-B55 protein of mouse, rat and human origin. PP2A-B55 Antibody (D-10) is available as both the non-conjugated anti-PP2A-B55 antibody form, as well as multiple conjugated forms of anti-PP2A-B55 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2Aα and PP2Aβ. The PP2A catalytic subunit associates with a variety of regulatory subunits. The B family of regulatory subunits (including B55, B56 and PR72/130 subfamilies) is believed to participate in substrate specificity and catalytic activity. PP2A-B55, also known as PP2A regulatory subunit subfamily B55 or PP2A-B1, is a B subfamily consisting of four B55 isoforms (α, β, γ and δ) encoded by four distinct genes.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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