Phosphodiesterase V Inhibitor II MF: C24H25N3O3
MW: 403.5
An inhibitor of phosphodiesterase.

Phosphodiesterase V Inhibitor II

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Ansökan Phosphodiesterase V Inhibitor II is an inhibitor of phosphodiesterase
Renhet: ≥97%
Molekylvikt: 403.5
Molekylär formel: C24H25N3O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Phosphodiesterase V Inhibitor II is a cell-permeable tetrahydro-β-carboline-hydantoin compound. Acts as a potent and highly selective PDE (phosphodiesterase V inhibitor).


Konferenser

Daugan, A., et al. 2003. J. Med. Chem. 46, 4533. Daugan, A., et al. 2003. J. Med. Chem. 46, 4525.

Physical State :
Solid
Solubility :
Soluble in DMSO (100 mg/ml), and ethanol.
LAGRING :
Store at 4° C
Melting Point :
273.14° C (Predicted)
Boiling Point :
584.75° C at 760 mmHg (Predicted)
Density :
1.34 g/cm3 (Predicted)
Refractive Index :
n20D 1.69 (Predicted)
IC50 :
PDE V: IC50 = 5 nM (bovine); Intracellular cGMP levels: EC5050 = 1 µM (ANF-treated RSMC); Recombinant PDE I & III: IC50 = > 10 µM (human); PDE II & IV: IC50 = > 10 µM (bovine)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD09037550
SMILES :
CCCCN1C(=O)C2CC3=C(C(N2C1=O)C4=CC=C(C=C4)OC)NC5=CC=CC=C35

Download SDS (MSDS)

Certificate of Analysis

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