Anti-PDCL3 Antibody (F-4) is a mouse monoclonal IgG2a (kappa light chain) PDCL3 antibody provided at 200 µg/ml
specific for an epitope mapping between amino acids 181-198 within an internal region of PDCL3 of human origin
Anti-PDCL3 Antibody (F-4) is recommended for detection of PDCL3 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-PDCL3 Antibody (F-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of PDCL3 (F-4): sc-515739.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for PDCL3 Antibody (F-4) for WB applications. These reagents are now offered in bundles with PDCL3 Antibody (F-4) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
PDCL3 Antibody (F-4) is a high quality monoclonal PDCL3 antibody (also designated PDCL3 antibody) suitable for the detection of the PDCL3 protein of mouse, rat and human origin. PDCL3 Antibody (F-4) is available as both the non-conjugated anti-PDCL3 antibody form, as well as multiple conjugated forms of anti-PDCL3 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. PDCL3 (phosducin-like 3), also known as VIAF1 (viral IAP-associated factor 1), VIAF, PHLP3 or HTPHLP, is a widely expressed protein that belongs to the phosducin-like family of proteins. Members of this family contain a conserved C-terminus and were initially thought function as modulators of heterotrimeric G proteins that specifically bound to the βγ subunits of G proteins, thereby neutralizing the subunit and inhibiting G protein-mediated signal transduction. It is now believed that the majority of phosducin-like family members associate with the cytosolic chaperonin complex (CCT) and regulate the folding of proteins. Localizing to the cytoplasm, PDCL3 does not appear to play a role in G protein signaling, but participates in the chaperone-assisted folding of proteins, such as β Tubulin and Actin, that are involved in the regulation of cell cycle progression. More specifically, PDCL3, when associated with CCT, represses the ATPase activity of CCT and ultimately disrupts the folding of the Actin or tubulin substrates.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
All trademarks are the property of their respective owners.
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn