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Oleic Acid, a monounsaturated fatty acid originally derived from Olea europaea, has been shown to be an anti-proliferative agent. This compound has also been reported to promote neuronal differentiation in murine cell cultures. Mechanistic studies suggest that these Oleic Acid effects are mediated by PPARβ. Furthermore, Oleic Acid has demonstrated the ability to stimulate an increase in secretion of collagen I, TGF-β secretion, and extracellular signal-regulated kinase1/2. Oleic Acid is an activator of PKC and CaMKII.
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See how others have used Oleic Acid. Click on the entry to view the PubMed entry .
PMID: # 28819452 Chen, L. et al. 2017. Theranostics. 7: 2634-2648.
PMID: # 19808663 Kansanen, E. et al. 2009. J. Biol. Chem. 284: 33233-33241.
PMID: # 32157714 J. Food Biochem. e13177.
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