Nalmefene hydrochloride CAS: 58895-64-0
MF: C21H25NO3•HCl
MW: 375.89
An opioid receptor antagonist.

Nalmefene hydrochloride (CAS 58895-64-0)

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Ansökan Nalmefene hydrochloride is an opioid receptor antagonist
CAS Nr: 58895-64-0
Molekylvikt: 375.89
Molekylär formel: C21H25NO3•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Nalmefene hydrochloride has been reported to be an opioid receptor antagonist. The opioid family of G-protein-coupled receptors contains three types of opioids; μ opioid receptor (MOR), δ opioid receptor (DOR), and κ opioid receptor (KOR).

Physical State :
Solid
Solubility :
Soluble in water (>25 mg/ml), DMSO (100 mM), and chloroform (0.13 mg/ml).
LAGRING :
Desiccate at room temperature
Boiling Point :
507.9° C at 760 mmHg (Predicted)
IC50 :
Kappa opioid receptor: IC50 <500 nM (human); Beta-galactosidase: EC5050 >31500 nM (Escherichia coli)
Ki Data :
Kappa opioid receptor: Ki= 0.12 nM (human); Mu opioid receptor: Ki= 0.29 nM (Rattus norvegicus); Mu opioid receptor: Ki= 0.44 nM (human); Kappa opioid receptor: Ki= 1.03 nM (human); Delta opioid receptor: Ki= 3.4 nM (Rattus norvegicus)
pK Values :
pKa: 9.38 (Predicted), 7.6, pKb: 7.68 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
QC7699000
PubChem CID :
Merck Index :
14: 6360
MDL Number :
MFCD07772293
SMILES :
C=C1CC[[email protected]]2([[email protected]]3CC4=C5[[email protected]]2([[email protected]]1OC5=C(C=C4)O)CCN3CC6CC6)O.Cl

Download SDS (MSDS)

Certificate of Analysis

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