Anti-NAB1 Antibody (A-8) is a mouse monoclonal IgG2b (kappa light chain) NAB1 antibody provided at 200 µg/ml
raised against amino acids 281-486 mapping at the C-terminus of NAB1 of human origin
Anti-NAB1 Antibody (A-8) is recommended for detection of NAB1 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-NAB1 Antibody (A-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of NAB1 (A-8): sc-137084.
m-IgGκ BP-HRP is the preferred secondary detection reagent for NAB1 Antibody (A-8) for WB applications. This reagent is now offered in a bundle with NAB1 Antibody (A-8) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
NAB1 Antibody (A-8) is a high quality monoclonal NAB1 antibody (also designated NAB1 antibody) suitable for the detection of the NAB1 protein of mouse, rat and human origin. NAB1 Antibody (A-8) is available as both the non-conjugated anti-NAB1 antibody form, as well as multiple conjugated forms of anti-NAB1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Transcriptional control is in part regulated by interactions between DNA-bound transcription factors, such as Egr1/NGFI-A, and coregulatory proteins, such as NAB (for NGFI-A-binding proteins). The evolutionarily conserved NAB proteins, NAB1 and NAB2, are corepressors of Egr1/NGFI-A. Both NAB1 and NAB2 contain an amino-terminal NAB-conserved domain 1 (NCB1), which is required for binding NGFI-A, and a carboxy-terminal NCD2, which is responsible for the repressor function of NAB proteins. NAB1 requires NGFI-A to gain access to DNA, indicating that NAB1 is an active repressor that works by a direct mechanism. NAB1, which is constitutively expressed, is localized exclusively in the nucleus and may play a role in controlling processes such as cell division, differentiation and apoptosis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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