Anti-Mucin 5B Antibody (5B#19-2E) is a mouse monoclonal IgG1 κ Mucin 5B antibody, cited in 12 publications, provided at 200 µg/ml
raised against a peptide mapping at the N-terminus of Mucin 5B of human origin
Anti-Mucin 5B Antibody (5B#19-2E) is recommended for detection of Mucin 5B of mouse, rat and human origin by WB, IP and IF
Mucin 5B Antibody (5B#19-2E) is available conjugated to agarose for IP; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Mucin 5B (5B#19-2E): sc-21768.
m-IgG Fc BP-HRP (mouse IgG Fc binding protein-HRP) and m-IgG1 BP-HRP (mouse IgG1 binding protein-HRP) are the preferred secondary detection reagents for Mucin 5B Antibody (5B#19-2E) for WB applications. These reagents are now offered in bundles with Mucin 5B Antibody (5B#19-2E) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Mucin 5B Antibody (5B#19-2E) is a high quality monoclonal Mucin 5B antibody (also designated mucin 5B oligomeric mucus/gel-forming antibody or MUC5B antibody) suitable for the detection of the Mucin 5B protein of mouse, rat and human origin. Mucin 5B Antibody (5B#19-2E) is available as both the non-conjugated anti-Mucin 5B antibody form, as well as multiple conjugated forms of anti-Mucin 5B antibody, including agarose, PE, FITC and multiple Alexa Fluor® conjugates. Mucins are a group of high molecular weight glycoproteins consisting of a mucin core protein and O-linked carbohydrates. The Mucin 5B gene, which contains a 3′ cis-element, is one of the four mucin genes mapped to human chromosome 11p15. Although Mucin 5B is the prominent human gallbladder mucin, it is also expressed and secreted in the colon. In addition, Mucin 5B is expressed in non-inflammed middle ears and normal esophagus, and is upregulated by chronic inflammation and highly secreted in the diseased middle ear. Mucin 5B is abnormally expressed in gastric carcinomatous tissues. Its expression in gastric cancer cells is controlled by a highly active distal promoter, which is upregulated by protein kinase C and repressed under the influence of methylation. Mucous differentiation and expression of Mucin 5B is retinoic acid- (RA) or retinol-dependent. RA control of mucin gene is mediated by the retinoid acid receptor RARα and, to a lesser extent, by RARγ. The correlation of mucin protein levels in human cervical mucous with the peak at midcycle suggests that mucin may be important in sperm transit to the uterus.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences