Anti-Mpi Antibody (B-2) is a mouse monoclonal IgG1 κ Mpi antibody, cited in 1 publications, provided at 200 µg/ml
raised against amino acids 1-164 mapping at the N-terminus of Mpi of human origin
Mpi Antibody (B-2) is recommended for detection of Mpi of human origin by WB, IP, IF, IHC(P) and ELISA
Anti-Mpi Antibody (B-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Mpi (B-2): sc-393484.
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Mpi Antibody (B-2) for WB and IHC(P) applications. These reagents are now offered in bundles with Mpi Antibody (B-2) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Mpi Antibody (B-2) is a high quality monoclonal Mpi antibody (also designated Mpi antibody) suitable for the detection of the Mpi protein of human origin. Mpi Antibody (B-2) is available as both the non-conjugated anti-Mpi antibody form, as well as multiple conjugated forms of anti-Mpi antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Mpi (mannose phosphate isomerase), also known as PMI (phosphomannose isomerase) or PMI1, is a 423 amino acid zinc metalloenzyme belonging to the mannose-6-phosphate isomerase type 1 family, and is expressed in all tissues, more abundantly in heart, brain and skeletal muscle. A steady supply of D-mannose derivatives, which are required for most glycosylation reactions, is maintained by Mpi. Localized to the cytoplasm, Mpi utilizes zinc as a cofactor and catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate. Mutations in the gene encoding Mpi lead to congenital disorder of glycosylation type 1B (CDG1B), also designated carbohydrate-deficient glycoprotein syndrome type Ib (CDGS1B), which is characterized by protein-losing enteropathy. Congenital disorders of glycosylation are metabolic deficiencies in glycoprotein biosynthesis that usually results in severe mental and psychomotor retardation.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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