MAVS Antibody (E-6) is a mouse monoclonal IgG1 κ, cited in 11 publications, provided at 200 µg/ml
raised against amino acids 1-300 mapping within an N-terminal cytoplasmic domain of MAVS of mouse origin
MAVS Antibody (E-6) is recommended for detection of MAVS of mouse origin by WB, IP, IF and ELISA
Anti-MAVS Antibody (E-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of MAVS (E-6): sc-365334.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MAVS Antibody (E-6) for WB applications. These reagents are now offered in bundles with MAVS Antibody (E-6) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
MAVS (mitochondrial antiviral-signaling protein), also known as IPS1, KIAA1271, VISA or CARDIF, is a 540 amino acid protein that contains one CARD domain and several transmembrane domains, and localizes to the outer mitochondrial membrane. Expressed throughout the body with highest ex-pression in liver, heart, placenta, skeletal muscle and peripheral blood leuk-ocytes, MAVS functions downstream of proteins, such as RIG-I, that detect double-stranded (ds) viral replication and is required for proper immune re-sponse against ds viral infection. MAVS is thought to activate pathways that lead to the induction of antiviral cytokines and may protect the cells from viral-induced apoptosis. MAVS function can be inactivated via cleavage by a protease complex that degrades the CARD and transmembrane domains, thereby preventing MAVS from interacting with other proteins. Three isoforms of MAVS are expressed due to alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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