Anti-MAFbx Antibody (F-9) is a mouse monoclonal IgG1 κ MAFbx antibody, cited in 37 publications, provided at 200 µg/ml
raised against amino acids 1-300 mapping at the N-terminus of MAFbx of human origin
Anti-MAFbx Antibody (F-9) is recommended for detection of MAFbx isoforms 1-3 and FBXO25 isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-MAFbx Antibody (F-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of MAFbx (F-9): sc-166806.
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for MAFbx Antibody (F-9) for WB applications. These reagents are now offered in bundles with MAFbx Antibody (F-9) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
MAFbx Antibody (F-9) is a high quality monoclonal MAFbx antibody (also designated Muscle atrophy F-box protein antibody, MAFbx antibody, ATROGIN1 antibody, Atrogin-1 antibody, F-box protein 32 antibody, Fbx32 antibody, F-box only protein 32 antibody, or FBXO-32 antibody) suitable for the detection of the MAFbx protein of mouse, rat and human origin. MAFbx Antibody (F-9) is available as both the non-conjugated anti-MAFbx antibody form, as well as multiple conjugated forms of anti-MAFbx antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Muscle atrophy F-box (MAFbx) is an E3 ubiquitin ligase that initiates ATP-dependent ubiquitin-mediated proteolysis and promotes muscle atrophy. MAFbx transcript is abundant in cardiac and skeletal muscle undergoing atrophy. MAFbx -/- mice are resistant to muscle atrophy. MAFbx is thought to recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation during skeletal muscle atrophy. It interacts with MyoD by ubiquitination via a sequence found in transcriptional coactivators and therefore may play an important role in the course of muscle differentiation by determining the abundance of MyoD. MAFbx is specifically expressed in cardiac and skeletal muscle.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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