Anti-MAAI Antibody (H-1) is a mouse monoclonal IgG1 (kappa light chain) MAAI antibody provided at 200 µg/ml
specific for an epitope mapping between amino acids 151-209 within an internal region of MAAI of human origin
Anti-MAAI Antibody (H-1) is recommended for detection of MAAI of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-MAAI Antibody (H-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of MAAI (H-1): sc-271411.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MAAI Antibody (H-1) for WB and IHC(P) applications. These reagents are now offered in bundles with MAAI Antibody (H-1) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
MAAI Antibody (H-1) is a high quality monoclonal MAAI antibody (also designated MAAI antibody) suitable for the detection of the MAAI protein of mouse, rat and human origin. MAAI Antibody (H-1) is available as both the non-conjugated anti-MAAI antibody form, as well as multiple conjugated forms of anti-MAAI antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. In humans, maleylacetoacetate isomerase (MAAI, also known as GSTZ1-1) catalyzes the conversion of maleylacetoacetate to fumarylacetoacetate, the fifth step in the phenylalanine/phenylacetate degradation pathway. Deficiencies in other steps of this pathway cause metabolic diseases, including type I tyrosinemia and phenylketonuria. The glutathione S-transferases (GSTs) are found in all aerobic organisms and catalyze the conjugation of glutathione to a wide variety of electrophilic substrates. By sequence alignment and phylogenetic analysis, a new subgroup of GST-like proteins from human, C. elegans, and carnation were identified. Human MAAI is 38% and 49% identical to the carnation and C. elegans proteins, respectively. Recombinant human MAAI is a dimer. The enzyme exhibits limited activity with known GST substrates. Western blot analysis indicates that MAAI is most abundant in liver, with lower levels detected in skeletal muscle and brain. The gene which encodes MAAI maps to human chromosome 14q24.3.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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