Anti-M-RIP Antibody (E-1) is a mouse monoclonal IgG1 (kappa light chain) M-RIP antibody provided at 200 µg/ml
raised against amino acids 668-760 mapping within an internal region of M-RIP of human origin
Anti-M-RIP Antibody (E-1) is recommended for detection of M-RIP of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-M-RIP Antibody (E-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of M-RIP (E-1): sc-515720.
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for M-RIP Antibody (E-1) for WB applications. These reagents are now offered in bundles with M-RIP Antibody (E-1) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
M-RIP Antibody (E-1) is a high quality monoclonal M-RIP antibody (also designated M-RIP antibody) suitable for the detection of the M-RIP protein of mouse, rat and human origin. M-RIP Antibody (E-1) is available as both the non-conjugated anti-M-RIP antibody form, as well as multiple conjugated forms of anti-M-RIP antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. M-RIP (myosin phosphatase Rho interacting protein), also known as MPRIP, p116Rip, RIP3 or RHOIP3, is a 1,025 amino acid cytoplasmic and cytoskeletal protein that is required for regulation of the actin cytoskeleton. M-RIP colocalizes with myosin binding subunit (MBS) to regulate the phosphorylation of myosin light chain, and colocalizes with F-actin through its N-terminus in the cytoskeleton. M-RIP also interacts with and RhoA at actin stress fibers via its adjacent coiled coil domains. M-RIP is highly expressed in ovary, with moderate levels found in brain, heart, liver, lung, skeletal muscle, testis and kidney. M-RIP depletion causes an increase of stress fibers in smooth muscle cells, whereas M-RIP over-expression causes disassembly of stress fibers in neuronal cells. Containing two PH domains, M-RIP has multiple phosphorylated serine and threonine residues and exists as three isoforms which are produced by alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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