LYPLA2 Antibody (B-12) is a mouse monoclonal IgG2a (kappa light chain) provided at 200 µg/ml
specific for an epitope mapping between amino acids 169-187 of LYPLA2 of human origin
Anti-LYPLA2 Antibody (B-12) is recommended for detection of LYPLA2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
Anti-LYPLA2 Antibody (B-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of LYPLA2 (B-12): sc-390546.
At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for LYPLA2 Antibody (B-12). This work is in progress.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The multifunctional lysophospholipids (detergent-like intermediates) found in various biological membranes are regulated by the enzymatic activity of lysophospholipases. Increased levels of lysophospholipids are associated with a host of diseases, including hyperlipidemia and atherosclerosis. LYPLA1 (lysophospholipase 1), also known as APT1 or LPL1, and LYPLA2 (lysophospholipase 2) are lysophospholipases that localize to the cytoplasm and belong to the AB hydrolase 2 family. Both LYPLA1 and LYPLA2 function to enzymatically hydrolyze fatty acids from S-acetylated cysteine residues on a variety of monomeric and micellar substrates, such as H-Ras. Due to their ability to catalytically regulate the overall concentration of lysophospholipids in cellular membranes, LYPLA1 and LYPLA2 may play a crucial role in the development of lysophospholipid-associated disorders. LYPLA1 and LYPLA2 exist as multiple alternatively spliced isoforms that are expressed in tissues throughout the body.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
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To place an order using RMB or to ship to mainland China, please visit www.scbio.cn