Integrin α6/ITGA6/CD49f Antibody (4F10) is a mouse monoclonal IgG2b κ, cited in 3 publications, provided at 200 µg/ml
raised against SW1222 colorectal cell line of human origin
recommended for detection of Integrin α6 of mouse, rat and human origin by WB, IP, IF and FCM
available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
See Integrin α6/ITGA6/CD49f (F-6): sc-374057 for Integrin α6/ITGA6/CD49f antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Integrin α6/ITGA6/CD49f Antibody (4F10) for WB applications. These reagents are now offered in bundles with Integrin α6/ITGA6/CD49f Antibody (4F10) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.