Ilimaquinone CAS: 71678-03-0
MF: C22H30O4
MW: 358.47
An ADP-ribosylation factor (ARF) and β-COP to the Golgi membrane inhibitor.

Ilimaquinone (CAS 71678-03-0)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 150ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: 3-[(Decahydro-1β,2β,4αβ-trimethyl-5-methylene-1-naphthyl)methyl]-2-hydroxy-5-methoxybenzoquinone;Imaquinone
Ansökan An ADP-ribosylation factor (ARF) and β-COP to the Golgi membrane inhibitor
Momsregistreringsnummer :: 71678-03-0
Purity: ≥98%
Molecular Weight: 358.47
Molecular Formula: C22H30O4
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Ilimaquinone is a natural marine metabolite shown to have antiinflammatory, antimicrobial, and antimitotic properties. Ilimaquinone has also been described to block diptheria toxin and the cytotoxicity of ricin. Golgi membrane studies reveal that exposure to ilimaquinone results in the formation of vesiculated Golgi membranes and blockage of the secretory pathway, which can be reversed with the removal of ilimaquinone. Additionally, ilimaquinone has been shown to block the association of the ADP-ribosylation factor (ARF) and β-COP to the Golgi membrane, and depolarize cytoplasmic microtubules. Further studies report that the vesiculation of Golgi membranes through Ilimaquinone takes place by the activation of heterotrimeric G proteins. Biochemical assays from HIV studies suggest that ilimaquinone belongs to a group of marine metabolites with anti-HIV activity. Ilimaquinone studies suggest that it has the ability to induce anti-proliferative affects through GADD153-mediated pathway modifications.


1. Takizawa, P.A., et al. 1993. Cell. 73: 1079-1090. PMID: 8513494
2. Veit, B., et al. 1993. J. Cell Biol. 122: 1197-1206. PMID: 8104190
3. Jamora, C., et al. 1997. Cell. 91: 617-626. PMID: 9393855
4. Dinter, A., et al. 1998. Histochem. Cell Biol. 109: 571-590. PMID: 9681636
5. Radeke, H.S., et al. 1999. Chem. Biol. 6: 639-647. PMID: 10467129
6. Tziveleka, L.A., et al. 2003. Curr Top Med Chem. 3: 1512-1535. PMID: 14529524
7. Lu, P.H., et al. 2007. Eur. J. Pharmacol. 556: 45-54. PMID: 17140562

Physical State :
Solubility :
Soluble in DMSO (25 mg/ml), and ethanol (25 mg/ml).
Store at -20° C
Melting Point :
204.22° C (Predicted)
Boiling Point :
~478.4° C at 760 mmHg (Predicted)
Density :
~1.1 g/cm3 (Predicted)
Refractive Index :
n20D 1.55
IC50 :
P388: IC50 = 0.2 ug/ml (Mus musculus); A549: IC50 = 0.4 ug/ml (human); A2780: IC50 = 10.9 µM (human); Adenosylhomocysteinase: IC50 = 40 µM (human)
pK Values :
pKa: 2.92
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
Merck Index :
14: 4898
MDL Number :
C[[email protected]]1CC[[email protected]]2([[email protected]]([[email protected]]1(C)CC3=C(C(=O)C=C(C3=O)OC)O)CCCC2=C)C

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

Ilimaquinone  Produkt Citat

See how others have used Ilimaquinone. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 27281477  Massarweh, A. et al. 2016. J. Lipid Res. 57: 1477-91.

Citations 1 to 1 of 1 total
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 148ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 9ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.