Anti-hnRNP U Antibody (3G6) is a mouse monoclonal IgG1 κ hnRNP U antibody, cited in 41 publications, provided at 200 µg/ml
raised against recombinant full length protein of hnRNP U of human origin
Anti-hnRNP U Antibody (3G6) is recommended for detection of hnRNP U of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-hnRNP U Antibody (3G6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of hnRNP U (3G6): sc-32315.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for hnRNP U Antibody (3G6) for WB and IHC(P) applications. This reagent is now offered in a bundle with hnRNP U Antibody (3G6) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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hnRNP U Antibody (3G6) is a high quality monoclonal hnRNP U antibody (also designated HNRNPU antibody, GRIP120 antibody, orp120 antibody) suitable for the detection of the hnRNP U protein of mouse, rat and human origin. hnRNP U Antibody (3G6) is available as both the non-conjugated anti-hnRNP U antibody form, as well as multiple conjugated forms of anti-hnRNP U antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. RNA polymerase II transcripts are complexed with hnRNP (heterogeneous nuclear ribonucleoprotein) proteins, which are involved in several aspects of hnRNA maturation and transport. The hnRNP particle U (also designated SP120 and SAF-A for scaffold attachment factor) is an abundant nucleoplasmic phosphoprotein and the largest of the major hnRNP proteins. hnRNP U is specifically involved in pre-mRNA processing and is directly bound to both RNA and DNA. Specifically, hnRNP U has a high affinity to the SAR (scaffold attachment region) of DNA. hnRNP U also functions as an RNA polymerase elongation inhibitor by inhibiting TFIIH-mediated phosphorylation of the carboxy-terminal domain of Pol II. Identical to GRIP120, hnRNP U also associates with glucocorticoid receptors to inhibit glucocorticoid induction.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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