Anti-hnRNP Q Antibody (I8E4) is a mouse monoclonal IgG1 κ hnRNP Q antibody, cited in 12 publications, provided at 200 µg/ml
raised against recombinant hnRNP-Q of human origin
hnRNP Q Antibody (I8E4) is recommended for detection of hnRNP Q of mouse, rat, human and Xenopus origin by WB, IP and IF
Anti-hnRNP Q Antibody (I8E4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of hnRNP Q (I8E4): sc-56703.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred secondary detection reagent for hnRNP Q Antibody (I8E4) for WB applications. This reagent is now offered in a bundle with hnRNP Q Antibody (I8E4) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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hnRNP Q Antibody (I8E4) is a high quality monoclonal hnRNP Q antibody (also designated SYNCRIP antibody, or HNRNPQ antibody)suitable for the detection of the hnRNP Q protein of mouse, rat, human and Xenopus laevis origin. hnRNP Q Antibody (I8E4) is available as both the non-conjugated anti-hnRNP Q antibody form, as well as multiple conjugated forms of anti-hnRNP Q antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Pre-mRNA splicing is a critical step in the posttranscriptional regulation of gene expression. Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) is involved in RNA processing and is necessary for efficient pre-mRNA splicing. hnRNP is widely expressed and developmentally regulated. hnRNP Q interacts with survival motor neuron protein (SMN). Loss of function of SMN results in spinal muscular atrophy, a common neurodegenerative disease. The most common deletion in SMN genes disrupts the interaction between SMN and hnRNP Q. hnRNP Q is upregulated after midnight, and this upregulation correlates with an abrupt decline in AANAT, the key enzyme in melatonin synthesis. Rhythmic AANAT mRNA degradation mediated in part by hnRNP Q implicates this enzyme in the regulation of circadian oscillation.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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