Anti-hnRNP K Antibody (D-6) is a mouse monoclonal IgG2a κ hnRNP K antibody, cited in 65 publications, provided at 200 µg/ml
raised against amino acids 1-300 of hnRNP K of human origin
Anti-hnRNP K Antibody (D-6) is recommended for detection of hnRNP K of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-hnRNP K Antibody (D-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of hnRNP K (D-6): sc-28380.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for hnRNP K Antibody (D-6) for WB and IHC(P) applications. This reagent is now offered in a bundle with hnRNP K Antibody (D-6) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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hnRNP K Antibody (D-6) is a high quality monoclonal hnRNP K antibody (also designated HNRNPK antibody) suitable for the detection of the hnRNP K protein of mouse, rat and human origin. hnRNP K Antibody (D-6) is available as both the non-conjugated anti-hnRNP K antibody form, as well as multiple conjugated forms of anti-hnRNP K antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of poly-peptides that contribute to mRNA transcription and pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA Polymerase II. There are approximately 20 known hnRNP proteins and their complexes are the major constituents of the spliceosome. The majority of hnRNP protein are localized to the nucleus, however some shuttle between the nucleus and the cytoplasm, such as hnRNP K. hnRNP K recruits a variety of molecular partners through two K homologous (KH) domains, which are required for protein-protein interactions. hnRNP K also contains several potential phosphorylation sites, including Ser 302, the major site of PKCd phosphorylation, which are thought to regulate various cellular functions, including sequence-specific DNA binding, transcription, RNA binding and nucleocytoplasmic shuttling.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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