Anti-hnRNP H3 Antibody (D-4) is a mouse monoclonal IgG1 κ hnRNP H3 antibody, cited in 1 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 155-185 within an internal region of hnRNP H3 of human origin
Anti-hnRNP H3 Antibody (D-4) is recommended for detection of hnRNP H3 isoforms 1, 2, 3, 4, 5 and 6 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-hnRNP H3 Antibody (D-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of hnRNP H3 (D-4): sc-376416.
m-IgG1 BP-HRP (mouse IgG1 binding protein-HRP) and m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) are the preferred secondary detection reagents for hnRNP H3 Antibody (D-4) for WB and IHC(P) applications. These reagents are now offered in bundles with hnRNP H3 Antibody (D-4) (see ordering information below).
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Labware ships FedEx Ground free of charge to the contiguous US
hnRNP H3 Antibody (D-4) is a high quality monoclonal hnRNP H3 antibody (also designated HNRNPH3 antibody, or HNRPH3 antibody) suitable for the detection of the hnRNP H3 protein of mouse, rat and human origin. hnRNP H3 Antibody (D-4) is available as both the non-conjugated anti-hnRNP H3 antibody form, as well as multiple conjugated forms of anti-hnRNP H3 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to mRNA transcription and pre-mRNA processing, as well as mature mRNA transport to the cytoplasm and translation. hnRNPs also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP proteins, and their complexes are the major constituents of the spliceosome. The majority of hnRNP proteins are localized to the nucleus; however some shuttle between the nucleus and the cytoplasm. hnRNPs F and H are highly related factors that preferentially associate with poly(rG) regions on RNA. hnRNP H3, also known as hnRNP 2H9, is a 346 amino acid protein involved in RNA processing, as well as early heat shock-inducing splicing arrest. hnRNP H3 contains two RNA recognition motif (RRM) domains, which include locations for binding single-stranded RNA. hnRNP H3 is expressed as six isoforms generated by alternative splicing of the pre-mRNA.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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