Anti-FBL5 Antibody (G-11) is a mouse monoclonal IgG1 κ FBL5 antibody provided at 200 µg/ml
raised against amino acids 1-300 mapping at the N-terminus of FBL5 of human origin
Anti-FBL5 Antibody (G-11) is recommended for detection of FBL5 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-FBL5 Antibody (G-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of FBL5 (G-11): sc-390102.
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for FBL5 Antibody (G-11) for WB and IHC(P) applications. These reagents are now offered in bundles with FBL5 Antibody (G-11) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
FBL5 Antibody (G-11) is a high quality monoclonal FBL5 antibody (also designated FBL5 antibody) suitable for the detection of the FBL5 protein of mouse, rat and human origin. FBL5 Antibody (G-11) is available as both the non-conjugated anti-FBL5 antibody form, as well as multiple conjugated forms of anti-FBL5 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. FBL5 is a 691 amino acid protein encoded by the human gene FBXL5. FBL5 contains one 40 amino acid F-box region, making it a member of the F-box family. FBL5 also contains four LRR (leucine-rich repeats). F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signalling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. Localized near the nucleus in the cytoplasm, FBL5 is ubiquitously expressed and believed to recognize and bind to phosphorylated proteins to promote their ubiquitination and degradation.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences