Anti-ErbB3/HER3 Antibody (G-4) is a mouse monoclonal IgG2b κ ErbB3/HER3 antibody, cited in 28 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 1315-1342 at the C-terminus of ErbB-3 of human origin
Anti-ErbB3/HER3 Antibody (G-4) is recommended for detection of ErbB-3 of mouse, rat and human origin by WB, IP, IF, FCM and ELISA; also reactive with additional species, including and bovine and porcine
Anti-ErbB3/HER3 Antibody (G-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of ErbB3/HER3 (G-4): sc-7390.
m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ErbB3/HER3 Antibody (G-4) for WB applications. These reagents are now offered in bundles with ErbB3/HER3 Antibody (G-4) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
ErbB-3 Antibody (G-4) is a high quality monoclonal ErbB-3 antibody (also designated erb-b2 receptor tyrosine kinase 3 antibody or HER3 antibody) suitable for the detection of the ErbB-3 protein of mouse, rat and human origin. ErbB-3 Antibody (G-4) is available as both the non-conjugated anti-ErbB-3 antibody form, as well as multiple conjugated forms of anti-ErbB-3 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The EGF receptor family comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcinomas. Members of this receptor family include EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3) and ErbB-4 (HER4), which form either homodimers or heterodimers upon ligand binding. Full length ErbB-3 is overexpressed in human mammary tumors. The ErbB-3 gene also produces several alternative variants, including a secreted form which negatively regulates heregulin stimulated ErbB activation. ErbB-3 heterodimerizes with Neu and binds heregulin in order to activate phosphoinositide (PI) 3-kinase. The recruitment and activation of PI 3-kinase occurs via its interaction with phosphorylated YXXM motifs in the carboxy terminus of ErbB-3.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
All trademarks are the property of their respective owners.
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn