DNA-PK Inhibitor IV morpholino-salicylaldehyde acts as a potent, selective and ATP-competitive inhibitor of DNA-PK. It inhibits PI 3-K catalytic subunit p110-isozymes at higher concentrations and weakly inhibits a panel of several other kinases. DNA-PK Inhibitor IV is an inhibitor of PI 3-kinase p110 α, PI 3-kinase p110 β and PI 3-kinase p110 δ.
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