Anti-DMPK Antibody (9-RY26) is a mouse monoclonal IgG2a κ DMPK antibody, cited in 2 publications, provided at 100 µg/ml
raised against an internal region of DMPK of human origin
recommended for detection of DMPK of human origin by WB, IP and ELISA
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of DMPK (9-RY26): sc-134319.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for DMPK Antibody (9-RY26) for WB applications. These reagents are now offered in bundles with DMPK Antibody (9-RY26) (see ordering information below).
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possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
DMPK Antibody (9-RY26) is a high quality monoclonal DMPK antibody (also designated DMPK antibody) suitable for the detection of the DMPK protein of human origin. DMPK Antibody (9-RY26) is available as the non-conjugated anti-DMPK antibody. Myotonic dystrophy protein kinase (DMPK) is a multi-domain protein kinase found in muscle that is activated in response to G protein second messengers and proteolysis. DMPK is implicated in myotonic muscular dystrophy (DM), an autosomal dominant-inherited disorder that predominately affects skeletal and cardiac muscle and causes defects in cardiac conduction. DM arises through expansion of CTG repeats in the 3′-UTR of the DMPK gene. Mutant DMPK transcripts with an extended region of CUG repeats are retained in the nucleus. These transcripts also influence the expression of the DM locus-associated homeodomain protein (DMAHP)/SIX5, to mediate in part the DM phenotype. Other substrates for DMPK include myogenin, L-type calcium channels, and Phospholemman (PLM).
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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