DLD Antibody (D-8) is a mouse monoclonal IgG2a κ, cited in 2 publications, provided at 200 µg/ml
raised against amino acids 356-509 mapping at the C-terminus of DLD of human origin
recommended for detection of DLD of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for DLD Antibody (D-8) for WB and IHC(P) applications. These reagents are now offered in bundles with DLD Antibody (D-8) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
DLD (Dihydrolipoyl dehyrogenase or Dihydrolipoamide dehydrogenase), also known as GCSL (glycine cleavage system L protein), PHE3, DLDH or LAD, is a member of the class I pyridine nucleotide-disulfide oxidoreductase family. DLD is a flavin-dependent oxidoreductase and functions as a component of the α-keto acid dehydrogenase, the pyruvate dehydrogenase, the α-ketoglutarate dehydrogenase, the branched-chain α-keto acid dehydrogenase and as the L protein in the mitochondrial glycine cleavage system. DLD localizes to the mitochondrial matrix and exists as a monomer, homodimer or tetramer that is required for energy metabolism in all eukaryotes. More specifically, DLD generates NADH and lipoic acid from dihydrolipoic acid and NAD+. The DLD homodimer catalyzes the opposite reaction. Mutations in the gene encoding DLD can result in MSUD (maple syrup urine disease) and congenital infantile lactic acidosis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.