DICA (CAS 613665-26-2)

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See product citations (1)

Alternativa namn: 2-(2,4-Dichlorophenoxy)-N-(2-mercaptoethyl)acetamide

Ansökan DICA is an inhibitor of caspase-3 and caspase-7

CAS Nr: 613665-26-2

Renhet: 98%

Molekylvikt: 280.2

Molekylär formel: C₁₀H₁₁Cl₂NO₂S

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

* Refer to Certificate of Analysis for lot specific data (including water content).

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DICA is an inhibitor of caspase-3 and caspase-7 binding to an allosteric site and not to the active site. Caspases are proteins that are critical to regulating the apoptotic pathway. These proteins cleave enzymes and proteins that are necessary for cell survival, in turn inducing apoptosis.

Konferenser

1. Hardy, J.A. 2004. Proc. Natl. Acad. Sci. U.S.A. 101: 12461-12466. PMID: 15314233

Physical State :

Solid

Solubility :

Soluble in methanol, and DMSO.

LAGRING :

Store at -20° C

Melting Point :

167.31° C

Boiling Point :

480.17° C at 760 mmHg (Predicted)

Density :

1.36 g/cm³ (Predicted)

Refractive Index :

n²⁰_D 1.57 (Predicted)

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

PubChem CID :

448572

SMILES :

C1=CC(=C(C=C1Cl)Cl)OCC(=O)NCCS

Download SDS (MSDS)

SAMPLE Certificate of Analysis (COA)

DICA | CAS 613665-26-2 SAMPLE Certificate of Analysis

Certificate of Analysis

SAMPLE Certificate of Analysis (COA)

Catalog Number:sc-202135

Lot Number:SAMPLE

Product Name:DICA

Molecular Formula:C₁₀H₁₁Cl₂NO₂S

Molecular Weight:280.2

Test	Specification	Results
Appearance	White to off-white solid	White solid
Identification (¹H-NMR)	Consistent with standard reference	Complies
Purity (TLC)	≥ 98%	Complies
Melting Point	88 - 96°C	92 - 94 °C
Solubility	Soluble in methanol or DMSO.	Complies

TEST CONDITIONS

TLC Conditions: Ethyl acetate: Petroleum ether (50:50)