DDX43 Antibody (LW-M1): sc-134311

DDX43 Antibody (LW-M1) is an IgG_2a κ mouse monoclonal DDX43 antibody (also designated HAGE antibody) suitable for the detection of the DDX43 protein of human origin by WB, IP and ELISA. DDX43 Antibody (LW-M1) is available as the non-conjugated anti-DDX43 antibody. DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division. DDX43 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 43), also known as CT13 or HAGE, is a 648 amino acid protein that contains one KH domain, one helicase C-terminal domain and one helicase ATP-binding domain and belongs to the DEAD-box family. Expressed in testis and present at abnormally high levels in a variety of tumors, DDX43 is thought to function as an ATP-dependent RNA helicase that may play a role tumor transformation and metastasis.

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References:

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