D-α-Hydroxyglutaric acid disodium salt CAS: 103404-90-6
MF: C5H6O5•2Na
MW: 192.08

D-α-Hydroxyglutaric acid disodium salt (CAS 103404-90-6)

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Alternativa namn: Sodium (R)-2-hydroxypentanedioate, 2R)-2-Hydroxypentanedioic Acid Disodium Salt
Ansökan D-α-Hydroxyglutaric acid disodium salt is an α hydroxy acid and the product of the hydrolysis of (R)-5-oxo-2-tetrahydrofurancarboxylic acid.
CAS Nr: 103404-90-6
Renhet: ≥95%
Molekylvikt: 192.08
Molekylär formel: C5H6O52Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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D-α-Hydroxyglutaric acid disodium salt is an α hydroxy acid, which is formed from the hydrolysis of (R)-5-oxo-2-tetrahydrofurancarboxylic acid. In humans the enzyme Hydroxyacid-oxoacid transhydrogenase catalyzes the formation of D-α-Hydroxyglutaric acid disodium salt, whereas in bacteria it is catalyzed by 2-hydroxyglutarate synthase.


Konferenser

1. Reeves, H.C. and AJL, S.J. 1962. J. Bacteriol. 84: 186-187. PMID: 14491016

2.. Wolcott, R G., et al., 1974. The reversal of the myosin and actomyosin ATPase reactions and the free energy of ATP binding to myosin. Biochemical and biophysical research communications. 57(3): 709-16. PMID: 4275131

3. Androsov, V N., et al., 1988. [Experience in treating hereditary angioneurotic edema]. Terapevticheskiĭ arkhiv. 60(3): 120-2. PMID: 3388262

4. Lobanenkov, V V., et al., 1988. [The effect of cytosine methylation in TTGGA(N5)TCCAA sequence of 5′-flanking region if the chicken betaH-globin gene on the interaction with TGGCA-binding protein in vitro]. Doklady Akademii nauk SSSR. 301(5): 1248-50. PMID: 3229304

5. Mochizuki, K. 2001. Arch. Microbiol. 175: 430-434. PMID: 11491083

6. Koivunen, Peppi., et al., 2012. Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation. Nature. 483(7390): 484-8. PMID: 22343896

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in PBS (10 mg/ml).
LAGRING :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD00069573
SMILES :
C(CC(=O)[O-])C(C(=O)[O-])O.[Na+].[Na+]

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Certificate of Analysis

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D-α-Hydroxyglutaric acid disodium salt (CAS 103404-90-6)  Produkt Citat

See how others have used D-α-Hydroxyglutaric acid disodium salt (CAS 103404-90-6). Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 28647531  Sudhamalla, B.|Dey, D.|Breski, M.|Islam, K.| et al. 2017. Anal. Biochem. 534: 28-35.

PMID: # 26971564  Richarson, AD. et al. 2016. Elife. 5:

Citations 1 to 2 of 2 total
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