Cysteamine Hydrochloride (CAS 156-57-0)

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Alternativa namn: Beta-mercaptoethylamine hydrochloride; Decarboxycystine HCl; 2-Aminoethanethiol HCl; Cystaran

Ansökan Cysteamine Hydrochloride is an antioxidant and an inhibitor of DMBA-induced tumors

CAS Nr: 156-57-0

Renhet: ≥99%

Molekylvikt: 113.61

Molekylär formel: C₂H₇NS•HCl

Kompletterande information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

* Refer to Certificate of Analysis for lot specific data (including water content).

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Cysteamine Hydrochloride is the salt formulation of the decarboxylated form of the amino acid cysteine. Clinically, cysteamine hydrochloride is used in the treatment of radiation sickness and disorders of cysteine excretion. Cysteamine cleaves the disulfide bond with cystine to produce molecules that can escape the metabolic defect in cystinosis and cystinuria. It is believed to inhibit DMBA-induced tumors

Konferenser

Tatsuta M, Iishi H, Baba M, Taniguchi H. International Journal of Cancer. 48:605-8 (1991). IP C, Ganther HE. arcinogenesis. 13:1167-70 (1992). Tatsuta M, Lishi H, Baba M, Taniguchi H. International Journal of Cancer. 44:1008-11 (1989).

Appearance :

Crystalline powder

Physical State :

Solid

Solubility :

Soluble in water (400 mg/ml at 20° C), ethanol, methanol, DMSO, and alcohol (very soluble ).

LAGRING :

Store at 4° C

Melting Point :

67-71° C

Refractive Index :

n²⁰_D 1.49 (Predicted)

IC50 :

CEM-SS: EC₅₀50 = 41.6 µM; CEM-SS: IC₅₀ = 71 µM (human); Plasmodium falciparum: IC₅₀ = 200 µM

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

WGK Germany :

RTECS :

KJ0200000

PubChem CID :

9082

Merck Index :

14: 2779

MDL Number :

MFCD00012904

EC Number :

205-858-1

Beilstein Registry :

3590083

SMILES :

C(CS)N.Cl

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Certificate of Analysis

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Cysteamine Hydrochloride (CAS 156-57-0) Produkt Citat

See how others have used Cysteamine Hydrochloride (CAS 156-57-0). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 26860350 ACS Appl Mater Interfaces. 5804-12.

Citations 1 to 1 of 1 total

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