Anti-cyclin D2 Antibody (B-6) is a mouse monoclonal IgG2b κ cyclin D2 antibody, cited in 6 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 261-289 at the C-terminus of cyclin D2 of mouse origin
recommended for detection of cyclin D2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for cyclin D2 Antibody (B-6) for WB and IHC(P) applications. These reagents are now offered in bundles with cyclin D2 Antibody (B-6) (see ordering information below).
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
cyclin D2 Antibody (B-6) is a high quality monoclonal cyclin D2 antibody (also designated CCND2 antibody) suitable for the detection of the cyclin D2 protein of mouse, rat and human origin. cyclin D2 Antibody (B-6) is available as both the non-conjugated anti-cyclin D2 antibody form, as well as multiple conjugated forms of anti-cyclin D2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The proliferation of eukaryotic cells is controlled at specific points in the cell cycle, particularly at the G1 to S and the G2 to M transitions. It is well established that the Cdc2 p34-cyclin B protein kinase plays a critical role in the G2 to M transition while cyclin A associates with Cdk2 p33 and functions in S phase. Considerable effort directed towards the identification of G1 cyclins has led to the isolation of cyclin D, cyclin C and cyclin E. Of these, cyclin D corresponds to a putative human oncogene, designated PRAD1, which maps at the site of the Bcl-1 rearrangement in certain lymphomas and leukemias. Two additional human type D cyclins, as well as their mouse homologs, have been identified. Evidence has established that members of the cyclin D family function to regulate phosphorylation of the retinoblastoma gene product, thereby activating E2F transcription factors.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.