Crenolanib CAS: 670220-88-9
MF: C26H29N5O2
MW: 443.54
A selective inihibitor of PDGFRα.

Crenolanib (CAS 670220-88-9)

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Crenolanib is rated 5.0 out of 5 by 1.
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Alternativa namn: CP-868596
Ansökan Crenolanib is a selective inihibitor of PDGFRα
Momsregistreringsnummer :: 670220-88-9
Purity: ≥98%
Molecular Weight: 443.54
Molecular Formula: C26H29N5O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Crenolanib (CP-868569) is a potent, oral, selective inihibitor of PDGFRα, with IC50 with 10 nM in PDGFRα over-expressed CHO cells.

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in DMSO (89 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (7 mg/ml at 25 °C).
LAGRING :
Store at -20° C
Melting Point :
283.14° C (Predicted)
Boiling Point :
~676.6° C at 760 mmHg (Predicted)
Density :
~1.4 g/cm3 (Predicted)
Refractive Index :
n20D 1.70 (Predicted)
IC50 :
PDGFRα: IC50 = 2.1 nM; PDGFRβ: IC50 = 3.2 nM
pK Values :
pKb: 9.84 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
10366136
MDL Number :
MFCD21609260
SMILES :
CC1(COC1)COC2=CC3=C(C=C2)N(C=N3)C4=NC5=C(C=CC=C5N6CCC(CC6)N)C=C4

Download SDS (MSDS)

Certificate of Analysis

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