MF: C26H29N5O2 MW: 443.54 A selective inihibitor of PDGFRα.
Protein-Interacting Inhibitors, Activators & Substrates
Crenolanib (CAS 670220-88-9)
Crenolanib is a selective inihibitor of PDGFRα
C 26H 29N 5O 2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. *
Certificate of Analysis for lot specific data (including water content).
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Crenolanib (CP-868569) is a potent, oral, selective inihibitor of PDGFRα, with IC50 with 10 nM in PDGFRα over-expressed CHO cells.
Soluble in DMSO (89 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (7 mg/ml at 25 °C).
Store at -20° C
283.14° C (Predicted)
~676.6° C at 760 mmHg (Predicted)
20 D 1.70 (Predicted)
50 = 2.1 nM; PDGFRβ: IC 50 = 3.2 nM
b: 9.84 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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