Brompheniramine CAS: 86-22-6
MF: C16H19BrN2
MW: 319.24
A reuptake inhibitor of seratonin.

Brompheniramine (CAS 86-22-6)

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Ansökan Brompheniramine is a reuptake inhibitor of seratonin
CAS Nr: 86-22-6
Molekylvikt: 319.24
Molekylär formel: C16H19BrN2
Kompletterande information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Brompheniramine is a halogenated alkylamine antihistamine which also has antidepressant properties due to reuptake inhibition of seratonin. This compound has analgesic-sparing effects on opiod analgesics as well.


Konferenser

1. Park. S.J., et al. 2008. J Appl. Toxicol. 28: 104-111. PMID: 17516459

Physical State :
Liquid
Solubility :
Soluble in water (partly), dilute acids, benzene, and chloroform (66.7 mg/ml).
LAGRING :
Store at room temperature
Melting Point :
129.16° C (Predicted)
Boiling Point :
147.2-152.2° C at 0.5 mmHg
Density :
1.27 g/mL (Predicted)
Refractive Index :
n20D 1.58 (Predicted)
IC50 :
Serotonin transporter: IC50 = 0.3 µM (rat); Plasmodium falciparum: IC50 = 0.5 µM; HERG: IC50 = 0.89 µM (human); Norepinephrine transporter: IC50 = 4.7 µM (rat); Sodium channel alpha subunits; brain : IC50 = 11 µM (human)
pK Values :
pKb: 9.33 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD00865691
EC Number :
201-657-8
Beilstein Registry :
217066
SMILES :
CN(C)CCC(C1=CC=C(C=C1)Br)C2=CC=CC=N2

Download SDS (MSDS)

Certificate of Analysis

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