MW: 637.00 A potent, novel and selective inhibitor of human telomerase.
Inhibitors, Activators, Substrates
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A potent, novel and selective inhibitor of human telomerase
C 30H 36N 4O 4* 2CH 3COOH *
Certificate of Analysis for lot specific data (including water content).
BPPA is a potent, novel and selective inhibitor of human telomerase that has displayed strong cytotoxic activity against human carcinoma cell lines through a mechanism of action unrelated to telomerase inhibition.
1. Perry, P.J., et al. 1998. J. Med. Chem. 41: 3253-3260. PMID: 9703471
Soluble in water (110 mg/ml), DMSO (20 mg/ml), and ethanol (2 mg/ml).
Store at -20° C
Telomerase : IC
50 = 4.5 µM (human); Inhibit SKOV-3-cell growth: IC 50 = 2.1 µM; Inhibit CH1-cell growth: IC 50 = 14.5 µM; Inhibit A2780-cell growth: IC 50 = 2.45 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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