bPiDDB CAS: 525596-66-1
MF: C24H38Br2N2
MW: 514.38
An antagonist of the orthosteric neuronal AChR.

bPiDDB (CAS 525596-66-1)

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Ansökan bPiDDB is an antagonist of the orthosteric neuronal AChR
Momsregistreringsnummer :: 525596-66-1
Molecular Weight: 514.38
Molecular Formula: C24H38Br2N2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

BPiDDB is a neuronal nicotinic acetylcholine receptor (AChR) antagonist (IC50 values are 0.17, 0.25, 0.4, 4.8, 6.5, 8.2, 20 and 34 μM at α3β4, α1β1γδ, α3β4β3, α6β4β3, α7, α4β2, α3β2β3 and α6/3β2β3 receptors, respectively).

Physical State :
Solid
Solubility :
Soluble in water (100 mM), and DMSO (100 mM).
LAGRING :
Desiccate at room temperature
IC50 :
nAChR α3β4: IC50 = 0.17 µM; nAChR α1β1γδ, : IC50 = 0.25 µM; nAChR α3β4β3: IC50 = 0.4 µM; nAChR α6β4β3: IC50 = 4.8 µM; nAChR α7: IC50 = 6.5 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Certificate of Analysis

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